A 15-year-old boy presented with high fever, lymphadenopathy, hepatosplenomegaly, recurrent skin infections, silvery hair, and photophobia. Last year, he developed ataxia. The MOST characteristic finding in this condition is

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Pediatric Immunization NCLEX Questions Ricci Questions

Question 1 of 5

A 15-year-old boy presented with high fever, lymphadenopathy, hepatosplenomegaly, recurrent skin infections, silvery hair, and photophobia. Last year, he developed ataxia. The MOST characteristic finding in this condition is

Correct Answer: A

Rationale: Chédiak-Higashi syndrome (silvery hair, infections, ataxia) is characterized by neutropenia due to defective neutrophil granule function.

Question 2 of 5

Monoclonal antibodies (mAb) are antibodies with a wide range of clinically important applications, such as pregnancy tests, cancer diagnosis, and cancer treatment. These antibodies are and come from parent cell(s).

Correct Answer: D

Rationale: Monoclonal antibodies are identical, produced from a single parent cell (hybridoma), ensuring specificity for clinical applications.

Question 3 of 5

Which of the following is NOT a major feature (characteristic) of the adaptive immune system?

Correct Answer: D

Rationale: Speed is a feature of innate immunity, not adaptive, which is characterized by specificity, diversity, and memory.

Question 4 of 5

Which of the following is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR), and is also known as a cytotoxic T cell (CTL)?

Correct Answer: B

Rationale: CD8+ is a co-receptor on cytotoxic T cells (CTLs), aiding TCR recognition of MHC class I-antigen complexes.

Question 5 of 5

Which of the following is NOT true regarding the complement system?

Correct Answer: C

Rationale: The complement system attracts phagocytes to foreign material, not self cells, making option c incorrect.

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