A 14-year-old boy is brought to the physician for examination prior to participating on his school’s soccer team. Physical examination shows jaundice. Serum studies show a total bilirubin concentration of 2.5 mg/dL, ALT activity of 70 U/L, and ceruloplasmin concentration of 5 mg/dL (N=20-40). A slit-lamp examination shows the presence of brownish rings in the cornea, surrounding the iris. The most appropriate treatment at this time is a drug with which of the following mechanisms of action?

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Quizlet Lifespan Considerations for Nursing Pharmacology with Rationals Questions

Question 1 of 5

A 14-year-old boy is brought to the physician for examination prior to participating on his school’s soccer team. Physical examination shows jaundice. Serum studies show a total bilirubin concentration of 2.5 mg/dL, ALT activity of 70 U/L, and ceruloplasmin concentration of 5 mg/dL (N=20-40). A slit-lamp examination shows the presence of brownish rings in the cornea, surrounding the iris. The most appropriate treatment at this time is a drug with which of the following mechanisms of action?

Correct Answer: D

Rationale: Kayser-Fleischer rings, low ceruloplasmin, jaundice, and elevated ALT suggest Wilson’s disease, a copper accumulation disorder. Penicillamine or trientine, which increase urine copper excretion (D), are appropriate treatments to reduce copper overloaBilirubin reduction treats jaundice unrelated to copper, selenium and chloride are irrelevant, and lead excretion (E) applies to lead poisoning, not Wilson’s.

Question 2 of 5

What is characteristic of the oral route?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

The term 'biotransformation' includes the following:

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Half life (t 1/2) doesn’t depend on:

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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