A 13-year-old female presents with 3 months of easy bruisability and bone pain. Complete blood count shows extreme leukocytosis. She is diagnosed with ALL and begins a chemotherapy regimen. One of her chemotherapeutic drugs is cyclophosphamide. What should also be given to avoid a potentially serious side effect of cyclophosphamide?

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ATI Practice Exam Pharmacology The Endocrine System Questions

Question 1 of 5

A 13-year-old female presents with 3 months of easy bruisability and bone pain. Complete blood count shows extreme leukocytosis. She is diagnosed with ALL and begins a chemotherapy regimen. One of her chemotherapeutic drugs is cyclophosphamide. What should also be given to avoid a potentially serious side effect of cyclophosphamide?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

A 19-year-old man attempts suicide after failing all of his college courses. He goes home and takes more than 90 digoxin tablets (0.25 mg each), ingesting them about 3 h prior to presentation at the emergency department. He is brought to the hospital by his brother. Vital signs are as follows: pulse is 50 beats/minute, and the electrocardiogram indicates third-degree heart block. Serum electrolytes are normal. Which of the following is the most important therapy to initiate in this patient?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Which of the following drugs is most useful for the treatment of absence seizures?

Correct Answer: D

Rationale: Lamotrigine, a broad-spectrum antiepileptic, treats absence seizures by stabilizing sodium channels and inhibiting glutamate release, though less specific than ethosuximide. Topiramate and levetiracetam manage multiple seizure types but aren't first-line for absence. Tiagabine, a GABA reuptake inhibitor, may worsen absence seizures. Zonisamide has broad efficacy but less absence focus. While ethosuximide is gold standard, lamotrigine's utility in absence, especially in mixed epilepsies, and clinical evidence make it the most useful here among options.

Question 4 of 5

Which over-the-counter (OTC) antihistamine combination contains an analgesic property?

Correct Answer: D

Rationale: Actifed Plus combines acetaminophen (an analgesic) with antihistamine and decongestant, relieving pain alongside allergy symptoms. Sudafed PE and Triaminic contain chlorpheniramine and phenylephrine, no analgesics. Tavist has clemastine alone. Choice D's analgesic property distinguishes it, relevant for nurses advising on OTC options.

Question 5 of 5

The client takes diphenhydramine (Benadryl) but forgets to tell the physician about this drug when a monoamine oxidase inhibitor (MAOI) drug is prescribed for depression. What will the best assessment by the nurse reveal?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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