ATI RN
ASCP Hematology Questions Questions
Question 1 of 5
A 13-month-old girl presented with progressive pallor for the last 3 months. The mother noticed that she started to eat a non-nutritive and dirty substance. She is on breast feeding till this age. On examination, she is pale, apathetic looking, no LAP, no organomegaly, and no skin bleeds. Of the following, the MOST likely diagnosis is:
Correct Answer: A
Rationale: Iron deficiency anemia (A) fits pallor, pica, and prolonged breastfeeding without solids, common at this age.
Question 2 of 5
The increment in hemoglobin after instituting oral iron therapy for iron deficiency anemia is about
Correct Answer: D
Rationale: Hemoglobin rises by 0.1-0.3 gm/dl/day (E is closest) with effective iron therapy.
Question 3 of 5
Mentzer index of less than 12.5 suggests thalassemia trait, it represents
Correct Answer: A
Rationale: Mentzer index (A) = MCV/RBC; <12.5 indicates thalassemia trait vs. >13 for iron deficiency.
Question 4 of 5
Which liver protein plays a key role in iron homeostasis?
Correct Answer: D
Rationale: Hepcidin (D) regulates iron absorption and storage, key to homeostasis.
Question 5 of 5
The best treatment option for hereditary spherocytosis is
Correct Answer: A
Rationale: Splenectomy (A) is the definitive treatment for severe hereditary spherocytosis to reduce hemolysis.