ATI RN
Pediatric Immunization Test Questions Questions
Question 1 of 5
A 13-month-old girl presented with failure to thrive, repeated chest infection, and fatty offensive diarrhea. Hemoglobin level 8.8 gm/dl, platelate count 150/mm3, white blood cell count 3.500/mm3, with absolute neutrophil count (ANC) 500/μL. Of the following, the MOST likely diagnosis is
Correct Answer: D
Rationale: Shwachman-Diamond syndrome features neutropenia, pancreatic insufficiency (fatty diarrhea), and failure to thrive, matching this presentation.
Question 2 of 5
Which of the following is a large genomic region or gene family found in most vertebrates, playing an important role in immunity?
Correct Answer: B
Rationale: MHCs are a large gene family in vertebrates critical for presenting antigens to T cells, distinguishing them from HLAs (a subset of MHC in humans) and other options.
Question 3 of 5
Which of the following components of the innate immune system involves the release of histamine?
Correct Answer: D
Rationale: Tissue mast cells release histamine during innate responses, such as allergies or inflammation, unlike the other listed cells.
Question 4 of 5
Natural killer cells
Correct Answer: B
Rationale: NK cells lyse virally infected cells and tumor cells as part of innate immunity, without antigen presentation.
Question 5 of 5
What stage of an adaptive immune response involves secretion of antibody from a large plasma cell with extensive endoplasmic reticulum?
Correct Answer: C
Rationale: The effector phase includes antibody secretion by plasma cells, which have extensive ER for protein production.