A 10-year-old female with history of insidious onset of fatigue, malaise, and progressive muscle weakness, accompanied by low-grade fevers and scaly, red plaques are found across the knuckles, she is not able to sit up from a supine position, investigations revealed: elevated muscle enzymes (ALT, AST, LDH, CPK, and aldolase), EMG abnormalities: fasciculations, needle insertion irritability, and high-frequency discharges. Of the following, the MOST serious complication that can occurs in this patient is the development of