ATI RN
Microbiology Chapter 12 Test Bank Questions
Question 1 of 5
A 10-year-old child had the mantoux tuberculin test administered. 48 hours later a papule up to 8 mm in diameter appeared on the site of the injection. What type of hypersensitivity reaction developed after the tuberculin injection?
Correct Answer: A
Rationale: The correct answer is A: Type IV hypersensitivity reaction. This type of reaction is characterized by a delayed response involving T cells. In this case, the appearance of a papule after 48 hours indicates a delayed hypersensitivity reaction, which is typical of a Type IV reaction. The other choices are incorrect because: B: Arthus phenomenon is a localized immune complex-mediated reaction, not seen in tuberculin tests. C: Seroreaction typically involves antibodies reacting with soluble antigens, not seen in this scenario. D: Type II hypersensitivity reactions involve antibodies targeting specific cells or tissues, which is not the mechanism at play in this case.
Question 2 of 5
On the territory of a certain region the mass death of rodents was observed. It was assumed that it may be caused by plague agent. What serological reaction should be applied for quick determination of antigen of this epizootic agent?
Correct Answer: B
Rationale: The correct answer is B: Agglutination reaction. This is the most suitable serological reaction for the quick determination of the antigen of the epizootic agent causing mass rodent deaths. In agglutination reaction, antibodies cause the clumping of antigens, allowing for easy visual detection of the presence of the specific antigen. This is efficient for rapid diagnosis in cases of suspected infectious diseases like plague. A: Precipitation reaction is more suitable for identifying soluble antigens, not for quick determination of a specific antigen in this scenario. C: Reaction of passive hemagglutination is used for measuring the presence of antibodies, not antigens. D: Bordet-Gengou test is a specific test for the identification of Bordetella pertussis bacterium, not suitable for this scenario.
Question 3 of 5
A 40-year-old female farmworker has been diagnosed with brucellosis and administered causal chemotherapy. What group of drugs will be used for this purpose?
Correct Answer: A
Rationale: The correct answer is A: Antibiotic. Brucellosis is a bacterial infection, and antibiotics are the primary treatment to target and eliminate the bacteria causing the disease. Antibiotics such as doxycycline and rifampin are commonly used for brucellosis treatment. Donor immunoglobulin (B) is not used to treat brucellosis as it is not caused by a deficiency in antibodies. Inactivated therapeutic vaccine (C) is used for prevention, not for treating active infections. Antitoxic serum (D) is used to neutralize toxins produced by bacteria, not to directly kill the bacteria themselves in cases like brucellosis.
Question 4 of 5
On the 8th day since the patient was inoculated with antitetanic serum because of dirty wound of his foot he has developed rising temperature up to 380% , pains in the joints, rash and itch. The blood tests revealed leukopenia and thrombocytopenia. Allergic reaction of what type has developed in this case?
Correct Answer: D
Rationale: The correct answer is D: Immunocomplex. In this case, the patient's symptoms of fever, joint pains, rash, and itch along with leukopenia and thrombocytopenia indicate a serum sickness reaction. This is a type III hypersensitivity reaction where antigen-antibody complexes deposit in tissues, leading to inflammation and tissue damage. The symptoms typically occur 1-2 weeks after exposure to the antigen. Anaphylactic reaction (choice A) is immediate and involves IgE antibodies. Cytotoxic reaction (choice B) involves destruction of cells by antibodies. Delayed hypersensitivity (choice C) usually takes 48-72 hours to develop and involves T-cells. Therefore, the correct answer is D as it aligns with the symptoms and timeline of a type III hypersensitivity reaction.
Question 5 of 5
A laboratory received a food product that had been taken from the focus of food poisoning and presumably contained botulinum toxin. To identify the type of toxin, the neutralization reaction must be performed on white mice. What biological product is used in this reaction?
Correct Answer: A
Rationale: The correct answer is A: Antitoxic serum. In the neutralization reaction to identify botulinum toxin, antitoxic serum is used to neutralize the toxin in white mice. Antitoxic serum contains antibodies that specifically target and neutralize the botulinum toxin. Normal serum (B) does not contain the necessary antibodies to neutralize the toxin. Antibacterial serum (C) is not effective against toxins like botulinum. Diagnosticum (D) is a general term and does not specifically refer to the biological product required for this reaction.