ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
A 10 year old boy with glucose-6-phosphate dehydrogenase deficiency has typhoid fever, the best drug for treatment is:
Correct Answer: C
Rationale: Amoxicillin is safe in G6PD deficiency for typhoid (Salmonella typhi). Co-trimoxazole and chloramphenicol risk hemolysis, and ciprofloxacin is avoided in children.
Question 2 of 5
A patient develops severe, watery diarrhea, fever & abdominal pain. Clostridium difficile infection in the gut is confirmed. The antimicrobial therapy for this antibiotic-associated pseudomembranous colitis is:
Correct Answer: D
Rationale: Metronidazole or vancomycin treats C. difficile colitis; vancomycin is preferred for severe cases, and both are effective.
Question 3 of 5
Which of the following is the most effective agent in the treatment of Rickettsia, Mycoplasma, and Chlamydia infections?
Correct Answer: D
Rationale: Tetracycline (e.g., doxycycline) is effective against intracellular pathogens like Rickettsia, Mycoplasma, and Chlamydia.
Question 4 of 5
Hypersensitivity reaction is a common and serious complication to:
Correct Answer: D
Rationale: Penicillins and sulfonamides frequently cause hypersensitivity reactions (e.g., rash, anaphylaxis), unlike erythromycin.
Question 5 of 5
Cefoperazone is associated with a high risk of:
Correct Answer: B
Rationale: Cefoperazone inhibits vitamin K-dependent clotting factors, increasing bleeding risk with warfarin.