ATI RN
Pharmacology ATI Proctored Exam 2024 Questions
Question 1 of 5
Which statement regarding medication distribution within the body is accurate?
Correct Answer: C
Rationale: Lipid-soluble drugs distribute widely, crossing membranes like the blood-brain barrier easily, unlike water-soluble ones. The barrier blocks some, not all, drugs. High blood flow aids delivery, not hinders. Protein complexes limit free drug, not enable crossing. Lipid solubility enhances distribution, a pharmacokinetic truth.
Question 2 of 5
A patient who takes high-dose aspirin to treat arthritis will need to take prednisone to treat an acute flare of symptoms. What action will the nurse perform?
Correct Answer: D
Rationale: Prednisone is a corticosteroid medication that can cause side effects such as fluid retention, electrolyte imbalance, and increased blood pressure. On the other hand, high-dose aspirin, especially when taken for arthritis, can have blood-thinning effects that may also contribute to lowering blood pressure. Given these potential effects of both medications, the nurse should be vigilant for the development of hypotension in the patient. Monitoring for signs and symptoms of low blood pressure, such as dizziness, lightheadedness, and weakness, is crucial in this situation to ensure the patient's safety.
Question 3 of 5
Two days after admission, the nurse is reviewing laboratory results of the patient. Which is the most common electrolyte finding resulting from the administration of furosemide (Lasix)?
Correct Answer: C
Rationale: The most common electrolyte finding resulting from the administration of furosemide (Lasix) is hypokalemia. Furosemide is a loop diuretic that works by blocking the reabsorption of sodium and chloride in the ascending loop of Henle in the kidneys. This results in increased excretion of water and electrolytes, including potassium. Hypokalemia can lead to various complications such as cardiac arrhythmias, muscle weakness, and fatigue. Therefore, patients receiving furosemide should be closely monitored for potassium levels, and supplementation may be necessary to prevent and treat hypokalemia.
Question 4 of 5
A 35-year-old African American male in the military is hospitalized with an MRSA skin infection. The patient starts treatment with an antibiotic and becomes anemic and jaundiced. On peripheral blood smear, Heinz bodies are seen within red blood cells. What is the mechanism of action of the antibiotic given to this patient?
Correct Answer: D
Rationale: MRSA treatment causing anemia, jaundice, and Heinz bodies suggests dapsone (sulfa drug), which inhibits folic acid metabolism . Oxidative stress from dapsone in G6PD-deficient patients (common in African Americans) leads to hemolysis. Options and are macrolide and tetracycline mechanisms. Option is penicillin's action. RNA polymerase inhibition (E) is rifampin's. Dapsone's sulfa action fits the clinical picture, with hemolysis as a side effect, not its primary MRSA mechanism, but the question's focus on outcome aligns with folate pathway disruption.
Question 5 of 5
The diagnostic triad of morphine overdose consists of:
Correct Answer: D
Rationale: The diagnostic triad of morphine overdose includes coma, depressed respiration, and pinpoint pupils. Coma occurs due to the central nervous system depression caused by morphine. Depressed respiration is a common symptom of opioid overdose, leading to respiratory distress and potential respiratory failure. Pinpoint pupils, also known as miosis, are a classic sign of opioid overdose and result from the effect of morphine on the autonomic nervous system. These three symptoms together are characteristic of a morphine overdose and indicate a medical emergency that requires prompt treatment.