ATI RN
ATI Intro to Pharmacology Quizlet Questions
Question 1 of 5
A history of which of the following is a contraindication to short-term HRT to prevent menopausal vasomotor symptoms and menopausal vaginitis?
Correct Answer: B
Rationale: Short-term HRT (estrogen ± progestin) relieves menopausal symptoms. Depression isn't a contraindication; HRT may improve mood. Breast cancer is a absolute contraindication due to estrogen's proliferative risk, outweighing benefits. Hysterectomy allows estrogen-only HRT, bronchitis and eczema are unrelated. Breast cancer's link to estrogen drives this restriction, critical for safe hormone use.
Question 2 of 5
A patient is in an urgent care center and is receiving treatment for mild hyponatremia after spending several hours doing gardening work in the heat of the day. The nurse expects that which drug therapy will be used to treat this condition?
Correct Answer: B
Rationale: In the scenario described, the patient is experiencing hyponatremia, a condition where there is an imbalance of electrolytes in the body due to excess water intake or loss of sodium-rich fluids like sweat. In this case, the patient has developed mild hyponatremia likely due to the combination of gardening work and exposure to heat.
Question 3 of 5
This describes the relationship of the blood concentration attained with initial dosing and the dose of drug given:
Correct Answer: D
Rationale: The volume of distribution (Vd) is a pharmacokinetic parameter that describes the relationship of the blood concentration attained with initial dosing and the dose of drug given. It is a theoretical volume that indicates the extent of drug distribution in the body relative to its concentration in the bloodstream. A high volume of distribution suggests that the drug is extensively distributed throughout the tissues of the body, while a low volume of distribution indicates that the drug is largely confined to the bloodstream. Therefore, Vd is the correct answer in this scenario.
Question 4 of 5
A patient taking SMZ/TMP asks the nurse what the name means. The nurse replies sulfamethoxazole is combined with trimethoprim in SMZ/TMP to help the drug effectiveness. How does this work?
Correct Answer: D
Rationale: SMZ/TMP (sulfamethoxazole/trimethoprim) works synergistically to inhibit bacterial folate synthesis at two different steps, making it effective against a broad spectrum of gram-positive and gram-negative organisms. It does not act as an anesthetic (A), displace trimethoprim (B), or increase excretion in the bladder (C). The combination enhances antibacterial activity and reduces the risk of resistance.
Question 5 of 5
When administering the anticoagulant drug Warfarin, what is one of the two lab tests you should monitor to distinguish the effectiveness of the drug?
Correct Answer: B
Rationale: When administering the anticoagulant drug Warfarin, one of the two lab tests you should monitor to distinguish the effectiveness of the drug is the International Normalized Ratio (INR). INR measures the time it takes for blood to clot and is used to monitor the effects of Warfarin therapy. The target INR range for patients on Warfarin therapy varies depending on the indication for treatment, but in general, a higher INR indicates that the blood is taking longer to clot, which means the Warfarin is working effectively to prevent blood clots. Regular monitoring of the INR levels is essential to ensure that patients are receiving an appropriate dose of Warfarin to prevent both clotting and bleeding complications.