ATI RN
ATI Pharmacology Practice A 2023 Questions
Question 1 of 5
Which of the following receptor-ligand pathway is TRUE:
Correct Answer: C
Rationale: Insulin acts via tyrosine kinase receptors, not G-protein-coupled receptors, so that's false. Mineralocorticoids (e.g., aldosterone) bind intracellular receptors, not tyrosine kinase, making that incorrect. Vitamin D binds intracellular nuclear receptors, regulating gene transcription, a true statement and the correct pathway. Adrenaline acts via G-protein-coupled adrenergic receptors, not ligand-gated channels, so that's false. Platelet-derived growth factor uses tyrosine kinase, not cytokine receptors. Vitamin D's intracellular action is key to its role in calcium homeostasis, distinguishing it from membrane-bound receptor mechanisms.
Question 2 of 5
The nurse assesses the client might be experiencing toxicity from colchicine. Which statement by the client would most likely confirm the nurse's suspicion?
Correct Answer: B
Rationale: Colchicine toxicity causes GI distress-nausea, vomiting, pain-per overdose data, a hallmark sign. Joint pain is gout, not toxicity. Vision/taste changes or cramps aren't linked-GI rules. This confirms suspicion, per assessment.
Question 3 of 5
A 24-year-old sexually active woman presents to her primary care physician with vaginal itching and a greenish, frothy vaginal discharge. Her boyfriend is asymptomatic. She is prescribed metronidazole for Trichomonas vaginalis. Which of the following should be told to avoid while taking metronidazole?
Correct Answer: A
Rationale: Metronidazole treats Trichomonas vaginalis, and alcohol must be avoided. It inhibits aldehyde dehydrogenase, causing a disulfiram-like reaction (nausea, flushing). Aspirin , caffeine , grapefruit juice , and machinery (E) lack this interaction. This precaution prevents severe discomfort, ensuring treatment adherence.
Question 4 of 5
A mother asks the nurse when she should give her child cough medicine. What is the best response by the nurse?
Correct Answer: D
Rationale: Cough suppressants relieve dry, disruptive coughs , aiding rest. Green secretions need clearance, fever signals illness, and bronchitis may require expectorants. D targets appropriate use, making it the best response.
Question 5 of 5
the antidote for Warfarin is?
Correct Answer: B
Rationale: Warfarin is an oral anticoagulant that works by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver. Therefore, the antidote for Warfarin overdose or to reverse its effects is vitamin K. Vitamin K helps in replenishing the depleted vitamin K-dependent clotting factors, allowing the blood to clot normally again. Administering vitamin K helps in reversing the anticoagulant effects of Warfarin, preventing excessive bleeding or hemorrhage.