ATI RN
ATI Pharmacology Assessment 2 Questions
Question 1 of 4
Which of the following combinations of antiparkinsonian drugs is appropriate treatment plan?
Correct Answer: B
Rationale: Levodopa, the cornerstone of Parkinson's treatment, converts to dopamine in the brain. Carbidopa inhibits peripheral dopa decarboxylase, increasing levodopa's CNS availability and reducing side effects. Entacapone, a COMT inhibitor, prolongs levodopa's half-life by preventing its peripheral breakdown, enhancing efficacy. This trio targets dopamine synthesis and metabolism synergistically, a standard advanced-stage regimen. Amantadine lacks synergy with carbidopa/entacapone, focusing on NMDA antagonism. Pramipexole (dopamine agonist) with carbidopa/entacapone is less common, as carbidopa pairs with levodopa. Ropinirole and selegiline boost dopamine but miss levodopa's direct effect; entacapone's role weakens without levodopa. The levodopa-carbidopa-entacapone combination optimizes dopamine delivery, making it a clinically proven and appropriate plan.
Question 2 of 4
The patient with schizophrenia is sitting quietly in a chair. The patient does not respond much to what is happening and has a lack of interest in the environment. How does the nurse interpret this assessment?
Correct Answer: D
Rationale: Schizophrenia's negative symptoms include apathy and withdrawal, seen in quietness and disinterest . Depression needs more evidence. Voices suggest positive symptoms, absent here. Positive symptoms add behaviors, not subtract. D aligns with schizophrenia's clinical presentation, making it the correct interpretation.
Question 3 of 4
A client is prescribed prednisone for rheumatoid arthritis. Which side effect should the nurse teach the client to report immediately?
Correct Answer: C
Rationale: Prednisone, a corticosteroid, manages inflammation but risks serious side effects. Blurred vision may signal glaucoma or cataracts, ocular emergencies requiring immediate reporting to prevent vision loss. Increased appetite and weight gain are common, manageable effects of cortisol excess. Mood swings occur due to CNS effects but are less urgent unless severe. Blurred vision stands out as a rare but critical adverse reaction, linked to prednisone's long-term impact on intraocular pressure or lens opacity. Teaching this ensures early detection, aligning with corticosteroid monitoring where eye complications can escalate fast. Appetite, weight, and mood changes, while disruptive, don't match this urgency, making C the priority side effect for the client to report promptly.
Question 4 of 4
The following drugs are most commonly associated with nephrotoxicity:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.