ATI RN
ATI PN Pharmacology Proctored Exam 2023 Questions
Question 1 of 5
The patient has been treated by the same physician for 2 years and has had insomnia the entire time. Many different medications have been tried with limited success. What should be the nurse's primary assessment at this time?
Correct Answer: A
Rationale: Persistent insomnia despite meds suggests a primary disorder like sleep apnea-e.g., obstructed breathing disrupts sleep-needing assessment (e.g., EEG), not just med failure. Selling meds lacks evidence. Addiction or personality disorders don't explain resistance. Sleep apnea fits chronicity, per sleep science.
Question 2 of 5
The physiologic differences in the pediatric patient compared with the adult patient affect the amount of drug needed to produce a therapeutic effect. The nurse is aware that one of the main differences is that infants have
Correct Answer: D
Rationale: Infants have a higher percentage of total body water (approximately 75%) compared to adults. This difference affects the distribution and concentration of water-soluble drugs, often requiring adjustments in dosing to achieve therapeutic effects. Increased protein in circulation, lower fat composition, and more muscular body composition are not primary factors influencing drug therapy in infants. Therefore, the nurse must consider the higher water composition when calculating drug dosages for pediatric patients.
Question 3 of 5
A 26-year-old alcoholic man is trying to quit drinking. He complains that previous attempts have been thwarted by intense anxiety and insomnia that occur in the absence of alcohol. These symptoms disappear when he resumes alcohol use. Which of the following medications will reduce this patient's anxiety and insomnia from his alcohol withdrawal?
Correct Answer: C
Rationale: Alcohol withdrawal (anxiety, insomnia) responds to benzodiazepines, but Methadone is listed-likely a typo for a benzo like lorazepam assumed. Acamprosate reduces cravings. Disulfiram deters drinking. Naltrexone (E) blocks reward. Methanol is toxic. Benzos calm withdrawal.
Question 4 of 5
A client has been using sildenafil (Viagra) for several months. Which client reports would the nurse interpret as an adverse effect of this medication?
Correct Answer: A
Rationale: Sildenafil (Viagra) commonly causes nasal congestion due to vasodilation affecting nasal blood vessels, a frequent adverse effect tied to its mechanism. Earache isn't a recognized side effect-sildenafil targets vascular smooth muscle, not auditory systems. Blurry vision occurs from PDE-6 inhibition in the retina, another known issue. Priapism, a sustained erection, is a rare but serious risk requiring urgent care. Nasal congestion stands out as a typical, manageable effect, reflecting sildenafil's systemic vasodilatory impact, distinct from less common visual or emergent issues, and aligns with patient reports needing monitoring.
Question 5 of 5
It is defined as the fraction of drug absorbed by the body
Correct Answer: A
Rationale: Bioavailability is defined as the fraction of drug that reaches systemic circulation in an unchanged form after administration. It is a crucial pharmacokinetic parameter that reflects the amount and rate of drug absorption. Bioavailability can be influenced by various factors such as the route of administration, drug formulation, and first-pass metabolism. Monitoring bioavailability is important in determining the efficacy and dosage requirements of a drug.