Which of the following drugs has been associated with Reye's syndrome in children?

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Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions

Question 1 of 5

Which of the following drugs has been associated with Reye's syndrome in children?

Correct Answer: A

Rationale: Aspirin (choice A) is linked to Reye's syndrome, a rare liver/brain disorder in children post-viral infection. Acetaminophen (choice B), Ibuprofen (choice C), and Naproxen (choice D) aren't associated. This contraindication limits aspirin's pediatric use.

Question 2 of 5

Which of the following adverse effects of levodopa is not minimized by combining it with carbidopa

Correct Answer: A

Rationale: Carbidopa does not prevent dyskinesias caused by prolonged levodopa use.

Question 3 of 5

A 7-year-old boy is brought to the emergency department by his parents after being stung by a bee. The parents say that he is allergic to bee stings, and the patient is having great difficulty breathing. Epinephrine is administered immediately. His symptoms improve as molecules of epinephrine bind to β\(_2\)-receptors in bronchial smooth muscle. Which of the following describes a feature of β\(_2\)-receptors?

Correct Answer: A

Rationale: β\(_2\)-adrenergic receptors are G-protein-coupled receptors that have seven transmembrane domains, which is a characteristic feature of this receptor family.

Question 4 of 5

Losartan differs from enalapril in the following respect

Correct Answer: A

Rationale: Unlike ACE inhibitors like enalapril losartan does not increase bradykinin levels reducing the risk of cough and angioedema.

Question 5 of 5

A 57-year-old man with a seizure disorder takes anti-epileptic medications. His physician would like to use a medicine that is metabolized only by the CYP1A2 receptor. Which of the following agents would be preferred?

Correct Answer: C

Rationale: Felbamate is primarily metabolized by the CYP1A2 enzyme, making it a suitable choice for patients where CYP1A2 metabolism is desired.

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