Which finding would most accurately indicate that a therapeutic range for a medication had been reached?

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Question 1 of 5

Which finding would most accurately indicate that a therapeutic range for a medication had been reached?

Correct Answer: B

Rationale: Therapeutic range balances efficacy-treating the condition (indication)-with safety, avoiding serious side effects, a clinical goal. No adverse effects alone doesn't confirm efficacy. Dose amount doesn't ensure range. Effectiveness with lethal effects exceeds range. Achieving indication safely defines therapeutic success, per pharmacology.

Question 2 of 5

A 19-year-old man is brought to the emergency room after being found by the police to be disruptive in a shopping mall. He states that he is hearing voices and seeing Jesus Christ. The police apprehended him because he was acting violently. He arrives in the emergency department and is combative. His blood pressure is 190/90 mm Hg. His core body temperature is 39°C. The most likely explanation for these findings is overdose of which of the following?

Correct Answer: D

Rationale: Hallucinations, violence, hypertension, and hyperthermia suggest phencyclidine (PCP) overdose . PCP, an NMDA antagonist, causes dissociative psychosis and sympathetic stimulation. Alcohol sedates, cocaine lacks hallucinations, marijuana doesn't cause violence, and Quaaludes (E) sedate. PCP's unique profile fits this acute, agitated presentation.

Question 3 of 5

The following drugs are effectively administered by the rectal route to produce their systemic effect:

Correct Answer: A

Rationale: Indometacin, when administered rectally, bypasses first-pass metabolism, allowing rapid systemic absorption and therapeutic effect.

Question 4 of 5

Meperidine hydrochloride (Demerol) is given to a client who is experiencing post-operative pain. Which of the following are the side effects of the medication, except?

Correct Answer: B

Rationale: Meperidine hydrochloride (Demerol) is an opioid analgesic commonly used for post-operative pain management. The common side effects of meperidine include tremors, sweating, and dizziness. Diarrhea is not a common side effect associated with meperidine use. Opioid analgesics like meperidine more commonly cause constipation rather than diarrhea. Therefore, choice B is the correct answer as the side effect of diarrhea is not typically seen with meperidine administration.

Question 5 of 5

Bisoprolol (Zebeta) would be the drug of choice for which patient with a diagnosis of hypertension?

Correct Answer: D

Rationale: Bisoprolol is the drug of choice for older adults. It is not associated with as many adverse effects in the elderly and regular dosing profiles can be used. This drug does not have an established pediatric dosage. Although the 37-year-old patient is an adult, there are additional choices for this patient, with a more favorable adverse effect profile. The nurse should consider age-related factors when selecting antihypertensive medications.

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