ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Trichloroethanol is the active metabolite of:
Correct Answer: D
Rationale: Chloral hydrate (choice D) is metabolized to trichloroethanol, which depresses the CNS, inducing sedation. Morphine (choice A) metabolizes to active compounds like morphine-6-glucuronide, not trichloroethanol. Clorazepate (choice B) becomes desmethyldiazepam, a benzodiazepine. Phenobarbitone (choice C) is a barbiturate, not metabolized to trichloroethanol. This identifies Chloral hydrate's metabolic pathway, key for its hypnotic use.
Question 2 of 5
A 21-year-old woman presents to her primary care physician complaining of “feeling sleepy all the time.†Physical exam is normal, but she has a history of hay fever since she was 14 years old. You discover that she is currently taking medicine for her allergy but cannot remember the name. She says it controls her hay fever symptoms well. You suspect that her medication is causing her to feel sleepy. Which of the following would be most likely to cause drowsiness?
Correct Answer: C
Rationale: Doxylamine, an antihistamine, is known to cause drowsiness due to its sedative effects on the central nervous system.
Question 3 of 5
The arthritis therapy least likely to cause gastric ulceration is
Correct Answer: B
Rationale: Acetaminophen is not an NSAID and does not cause gastric ulceration.
Question 4 of 5
Buspirone is:
Correct Answer: D
Rationale: Buspirone (choice D), a 5-HT1A partial agonist, treats anxiety without sedation (choice A), isn't for insomnia (choice B), and has a slow onset (choice C incorrect), taking weeks. Its anxiolytic action offers a non-addictive alternative to benzodiazepines.
Question 5 of 5
The characteristic feature of phenytoin pharmacokinetics is
Correct Answer: C
Rationale: Phenytoin follows nonlinear (saturation) kinetics meaning small dose increases can cause disproportionate rises in blood levels.