ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Acute or chronic colchicine toxicity may be identified by which signs/symptoms?
Correct Answer: D
Rationale: Colchicine toxicity can lead to alopecia, bone marrow suppression (blood dyscrasias), and severe gastrointestinal effects such as diarrhea and vomiting.
Question 2 of 5
Trichloroethanol is the active metabolite of:
Correct Answer: D
Rationale: Chloral hydrate (choice D) is metabolized to trichloroethanol, which depresses the CNS, inducing sedation. Morphine (choice A) metabolizes to active compounds like morphine-6-glucuronide, not trichloroethanol. Clorazepate (choice B) becomes desmethyldiazepam, a benzodiazepine. Phenobarbitone (choice C) is a barbiturate, not metabolized to trichloroethanol. This identifies Chloral hydrate's metabolic pathway, key for its hypnotic use.
Question 3 of 5
Morphine can be used for all the following therapeutic indications EXCEPT:
Correct Answer: B
Rationale: Morphine treats MI pain (choice A), postoperative pain (choice C), and pulmonary edema (choice D) by reducing pain and preload. Head injury pain (choice B) contraindicates it due to respiratory depression and ICP risks. This exception guides safe use.
Question 4 of 5
Which of the following is useful in treatment of trigeminal neuralgia:
Correct Answer: D
Rationale: Carbamazepine (choice D), an anticonvulsant, treats trigeminal neuralgia by stabilizing sodium channels, reducing nerve firing. Phenylbutazone (choice A), an NSAID, and Morphine (choice B), an opioid, aren't first-line. Atropine (choice C), an anticholinergic, is irrelevant. Carbamazepine is the standard therapy.
Question 5 of 5
A 33-year-old woman who takes diazepam for anxiety disorder is currently enrolled in an online master's degree program in accounting. She states that she has attended all classes and studied for a final examination. She has never had this type of problem before. However, when she took the examination, she remembered nothing that she studied. What is the most likely explanation for this finding?
Correct Answer: B
Rationale: Diazepam, a benzodiazepine, can cause anterograde amnesia, impairing the ability to form new memories while on the medication.