A patient with a wound infection had Gram-positive cocci in clusters isolated from a wound culture. The organism was catalase-positive and coagulase-positive. What is the likely causative agent?

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Question 1 of 5

A patient with a wound infection had Gram-positive cocci in clusters isolated from a wound culture. The organism was catalase-positive and coagulase-positive. What is the likely causative agent?

Correct Answer: A

Rationale: 1. Gram-positive cocci in clusters suggest Staphylococcus species. 2. Catalase-positive and coagulase-positive characteristics match with Staphylococcus aureus. 3. Staphylococcus aureus is a common cause of wound infections due to its virulence factors. 4. Other choices are incorrect: B) S. epidermidis is coagulase-negative and a common contaminant, C) S. pyogenes is catalase-negative, D) Enterococcus faecalis is not typically associated with wound infections.

Question 2 of 5

A patient with a painful ulcer had a wound culture revealing Gram-negative rods with a characteristic 'safety pin' appearance. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Yersinia pestis. Y. pestis is a Gram-negative rod that exhibits a 'safety pin' appearance on staining due to bipolar staining. This bacterium is the causative agent of plague, which can present as painful ulcers known as buboes. Y. pestis is transmitted by fleas and can cause outbreaks in humans. Summary: - B: Francisella tularensis causes tularemia, not typically associated with painful ulcers. - C: Brucella abortus causes brucellosis, which does not typically present with painful ulcers. - D: Clostridium botulinum causes botulism, characterized by muscle weakness and paralysis, not painful ulcers.

Question 3 of 5

An infectious diseases hospital admitted a veterinarian with assumed brucellosis. What serologic test can confirm this diagnosis?

Correct Answer: A

Rationale: The correct answer is A: Wright's agglutination reaction. For brucellosis diagnosis, this test detects antibodies against Brucella species. Wright's test specifically targets agglutinins, which are produced in response to Brucella infection. The other choices are incorrect because: B: Widal's test is used for typhoid fever caused by Salmonella typhi. C: Ascoli's test is for pneumococcal infections. D: Weigl's test is used for typhus fever caused by Rickettsia prowazekii.

Question 4 of 5

Microscopic examination of pus from a wound revealed Gram-positive cocci in grape-like clusters. The bacteria were catalase- and coagulase-positive. Identify the microorganism.

Correct Answer: A

Rationale: Step 1: Gram-positive cocci in grape-like clusters suggest Staphylococcus. Step 2: Catalase-positive indicates Staphylococcus (negative for Streptococcus). Step 3: Coagulase-positive is specific for Staphylococcus aureus. Summary: B: Streptococcus pyogenes is catalase-negative. C: Enterococcus faecalis does not form grape-like clusters. D: Micrococcus luteus is catalase-positive but not coagulase-positive.

Question 5 of 5

A patient with a wound infection had a Gram-positive cocci isolated from the sample. The bacteria were catalase-positive and coagulase-positive. What is the likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Staphylococcus aureus. This is because Staphylococcus aureus is Gram-positive, catalase-positive, and coagulase-positive, which matches the characteristics described in the question. Staphylococcus epidermidis is also Gram-positive but is coagulase-negative. Streptococcus pneumoniae is Gram-positive but is catalase-negative. Enterococcus faecalis is Gram-positive but is catalase-negative and coagulase-negative. Therefore, based on the given information, Staphylococcus aureus is the likely causative agent of the wound infection.

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