ATI RN
ATI Nurs 180 Pharmacology Quiz Questions
Extract:
Question 1 of 5
A nurse is preparing to administer naloxone (Narcan). The nurse understands that this medication has a rapid first-pass inactivation. Which of the route should the nurse NOT administer this medication?
Correct Answer: C
Rationale: The correct answer is C: Oral (PO). Naloxone has a rapid first-pass inactivation when administered orally, as it gets extensively metabolized by the liver before reaching systemic circulation.
Therefore, administering naloxone orally would result in reduced effectiveness due to the liver's metabolism. Subcutaneous (
A), intravenous (
B), and intramuscular (
D) routes bypass the liver initially, allowing naloxone to reach systemic circulation quickly and effectively. Hence, these routes are suitable for administering naloxone in emergency situations where rapid action is required.
Question 2 of 5
Correct Answer:
Rationale:
Question 3 of 5
Correct Answer:
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Question 4 of 5
Correct Answer:
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Question 5 of 5
Correct Answer:
Rationale: