ATI RN
ATI Nurs 180 Phamacology Questions
Extract:
Question 1 of 5
The nurse is assigned a 49-year-old female client in the primary care office for a wellness visit. The nurse assesses the client, documents nurses notes, and reviews the medication administration record for potential interactions. The nurse should be most concern with the potential interaction between __________and _________.
Correct Answer: A,F
Rationale: St. John's wort is a potent inducer of cytochrome P450 enzymes, significantly reducing warfarin's effectiveness, increasing the risk of thromboembolic events.
Question 2 of 5
The nurse is preparing to administer medications to a 54-year old client. Which medications taken would be affected by the first-pass effect?
Correct Answer: C,E,F
Rationale: Oral medications like famotidine, acetaminophen, and diphenhydramine undergo first-pass metabolism in the liver, reducing bioavailability. Sublingual and IV routes bypass this effect.
Question 3 of 5
A nurse is preparing to administer a medication to a client who states, 'That looks different from the pill I usually take.' Which is the best response by the nurse?
Correct Answer: B
Rationale: Asking the client to describe their usual pill allows the nurse to verify the medication, address the client's concern, and ensure no error has occurred.
Question 4 of 5
A nurse is caring for a client who overdosed on morphine and has a respiratory rate of 6/min. Which medication should the nurse plan to administer?
Correct Answer: A
Rationale: Naloxone is an opioid antagonist that reverses morphine overdose effects, such as respiratory depression, restoring normal breathing.
Question 5 of 5
A client presents to the healthcare setting with a diagnosis of chronic liver failure. The nurse understands this will affect which step of pharmacokinetics?
Correct Answer: C
Rationale: Chronic liver failure impairs drug metabolism, as the liver is the primary site for metabolizing drugs, potentially leading to drug accumulation and toxicity.