ATI Pharmocology Exam Fletcher NRSG 106 | Nurselytic

Correct Answer: A

Rationale: The correct answer is A: Carbidopa prevents the breakdown of levodopa in the periphery. Levodopa is the precursor to dopamine, which is depleted in Parkinson's disease. However, levodopa is broken down in the periphery before it reaches the brain, where it is needed. Carbidopa inhibits the enzyme that breaks down levodopa in the periphery, allowing more levodopa to reach the brain and be converted to dopamine. This leads to better therapeutic effects with lower doses and fewer side effects.



Choices B, C, and D are incorrect.
Choice B is false because carbidopa is not a biologic precursor of dopamine, but rather it enhances the effectiveness of levodopa.
Choice C is incorrect because carbidopa does not allow for larger doses of levodopa; it allows for lower doses to be effective.
Choice D is incorrect because drug-food interactions exist with both levodopa alone and in combination therapy with carbidopa.

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