ATI Nurs 180 Phamacology | Nurselytic

Questions 25

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ATI Nurs 180 Phamacology Questions

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Question 1 of 5

A nurse reads in a drug information guide that PO morphine has a high first-pass effect. Which of the following would the nurse expect?

Correct Answer: A

Rationale: The correct answer is A. When a drug has a high first-pass effect, a significant portion of the drug is metabolized by the liver before reaching the systemic circulation when taken orally (PO).
Therefore, administering the drug through a nonenteral route (e.g., intravenous) bypasses the liver, leading to higher bioavailability and efficacy. Option B is incorrect because with a high first-pass effect, oral administration would result in lower effectiveness. Option C is incorrect as drug excretion and metabolism are distinct processes. Option D is incorrect because the liver, not the kidney, is primarily responsible for first-pass metabolism of drugs.

Question 2 of 5

Correct Answer:

Rationale:

Question 3 of 5

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Question 4 of 5

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Question 5 of 5

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