ATI Nurs 180 Pharmacology Quiz II | Nurselytic

Correct Answer: A

Rationale: The correct answer is A: Lactic acidosis. Zidovudine, an antiretroviral medication, has a black box warning for lactic acidosis, a potentially life-threatening condition. Zidovudine can cause mitochondrial toxicity leading to lactic acidosis. This complication can manifest with symptoms like nausea, vomiting, abdominal pain, and fatigue. It is crucial for the nurse to educate the client about these symptoms and to seek immediate medical attention if they occur. The other choices - uterine cancer, oral candidiasis, and thromboembolic events - are not black box warnings associated with zidovudine. Uterine cancer is not directly linked to zidovudine use, oral candidiasis is a common opportunistic infection in HIV but not a black box warning for zidovudine, and thromboembolic events are not a known severe adverse effect of zidovudine.

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