ATI RN
ATI N180 Pharmacology Exam Questions
Extract:
Question 1 of 5
A nurse is preparing to administer naloxone (Narcan). The nurse understands that this medication has a rapid first-pass inactivation. The nurse understands that naloxone (Narcan) be administered in all of the following routes EXCEPT for:
Correct Answer: A
Rationale:
Rationale: Naloxone has a rapid first-pass inactivation when administered orally due to extensive metabolism in the liver.
Therefore, it should not be given orally. Intravenous, intramuscular, and subcutaneous routes bypass the liver, allowing naloxone to reach systemic circulation directly for quick action. Administering naloxone orally would result in reduced effectiveness due to liver metabolism. Other choices are incorrect because they all bypass the liver, allowing for effective naloxone action.
Question 2 of 5
Correct Answer:
Rationale:
Question 3 of 5
Correct Answer:
Rationale:
Question 4 of 5
Correct Answer:
Rationale:
Question 5 of 5
Correct Answer:
Rationale: