ATI RN
ATI RN Pharmacology 2019 Questions
Extract:
Question 1 of 5
A nurse is caring for a client who is taking digoxin to treat heart failure. Which of the following factors predisposes this client to developing digoxin toxicity?
Correct Answer: C
Rationale: The correct answer is C: Taking a high-ceiling diuretic. High-ceiling diuretics can cause hypokalemia, which potentiates the toxic effects of digoxin. Low potassium levels increase the risk of digoxin toxicity as digoxin competes with potassium for binding sites on the sodium-potassium ATPase pump in cardiac cells. This competition can lead to an increase in intracellular calcium, resulting in cardiac toxicity.
Choice A: Taking an HMG CoA reductase inhibitor does not predispose the client to digoxin toxicity.
Choice B: Having a 10-year history of COPD is not directly related to digoxin toxicity.
Choice D: Having a prolapsed mitral valve is not a factor that predisposes the client to digoxin toxicity.
Question 2 of 5
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Question 3 of 5
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Question 4 of 5
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Question 5 of 5
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