ATI RN
ATI Pharmacology Final Exam 1 Questions
Extract:
Question 1 of 5
A client is receiving high doses of methotrexate and is experiencing severe bone marrow suppression. The nurse expects which intervention to be ordered with this drug to reduce this problem?
Correct Answer: B
Rationale: Methotrexate is a dihydrofolate reductase inhibitor which inhibits synthesis of building blocks for DNA synthesis and repair. Leucovorin rescue helps mitigate bone marrow suppression.
Question 2 of 5
A client arrives in the emergency department with severe chest pain. The client reports that the pain has been occurring off and on for a week now. Which assessment finding would indicate the need for cautious use of nitrates and nitrites?
Correct Answer: A
Rationale: Nitrates and nitrites are vasodilators and could worsen existing hypotension.
Question 3 of 5
Before beginning a client's therapy with selective serotonin reuptake inhibitor (SSRI) antidepressants, the nurse will assess for concurrent use of which medications or medication class?
Correct Answer: C
Rationale: SSRIs interact with NSAIDs, increasing bleeding risk.
Question 4 of 5
What is the nurse's priority action if extravasation of an antineoplastic drug occurs during intravenous (IV) administration?
Correct Answer: C
Rationale: Extravasation can cause severe damage and necrosis; stopping the infusion and leaving the catheter in place for aspiration is critical.
Question 5 of 5
A client is receiving her third course of chemotherapy. What will the nurse teach her about managing stomatitis, an adverse effect of this drug involving inflammation of the oral mucosa?
Correct Answer: A
Rationale: Daily mouth examination helps monitor stomatitis progression and complications.