ATI RN
ATI Pharmacology 2 Quiz Questions
Extract:
Question 1 of 5
Which of the following complaints by a man taking gentamycin would be most indicative that he is experiencing ototoxicity?
Correct Answer: B
Rationale: The correct answer is B because complaints of being unable to hear the television are indicative of ototoxicity, a known side effect of gentamycin affecting auditory function. This occurs due to damage to the cochlear and vestibular structures in the inner ear. Changes in mental status (
A) are more associated with neurotoxicity. An increase in BUN and creatinine (
C) are more indicative of kidney damage. Tingling of extremities (
D) is not typically associated with ototoxicity.
Question 2 of 5
The term 'mutations' refers to:
Correct Answer: A
Rationale: The correct answer is A: Permanent, inheritable changes to DNA. Mutations are alterations in the DNA sequence that can be passed down to offspring. This is essential for genetic diversity and evolution. Option B is incorrect as it refers to a pathogen. Option C is incorrect as it describes virulence. Option D is incorrect as it refers to an antibiotic.
Question 3 of 5
Which adverse effect unique to vancomycin is caused by histamine release?
Correct Answer: C
Rationale: The correct answer is C: Red-man syndrome. Vancomycin can cause histamine release, leading to red-man syndrome characterized by flushing, rash, and pruritus. This is not seen with the other options:
A) Discoloration of body fluids is due to impurities in vancomycin,
B) Ototoxicity is a potential side effect of aminoglycosides, not vancomycin, and
D) Nephrotoxicity is a concern with drugs like aminoglycosides and amphotericin B.
Therefore, the unique adverse effect of vancomycin caused by histamine release is Red-man syndrome.
Question 4 of 5
When asked if there are any regulatory controls on herbal or dietary supplements, the nurse responds to the client by informing him that herbal and dietary supplements are regulated by the:
Correct Answer: D
Rationale: The correct answer is D: Dietary Supplement Health and Education Act (DSHE
A). This act specifically regulates herbal and dietary supplements in the United States. Under DSHEA, manufacturers are responsible for ensuring the safety of their products and the FDA monitors compliance. The other choices are incorrect because: A (Food, Drug and Cosmetic Act) primarily regulates drugs and cosmetics, not dietary supplements; B (Joint Commission on the Accreditation of Healthcare Organizations) focuses on accreditation of healthcare organizations, not supplement regulation; C (Health and Human Services) is a government department responsible for various health-related issues, but not specifically supplement regulation.
Question 5 of 5
Which of the following is a legal requirement contained in the DSHEA?
Correct Answer: C
Rationale: The correct answer is C. The Dietary Supplement Health and Education Act (DSHE
A) requires dietary supplements to state that the product is not intended to diagnose, treat, cure, or prevent any disease. This is to ensure that consumers understand that dietary supplements are not meant to be used as medications.
Choice A is incorrect because the DSHEA does not mandate that herbal products contain only one active ingredient.
Choice B is incorrect as the DSHEA does not require manufacturers to demonstrate effectiveness before marketing.
Choice D is incorrect because while dietary supplements must be safe, they are not required to be tested for safety prior to marketing under the DSHEA.