ATI RN Pharmacology Exam | Nurselytic

Questions 49

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ATI RN Pharmacology Exam Questions

Extract:


Question 1 of 5

What does the term 'first pass effect' refer to?

Correct Answer: D

Rationale: The term 'first pass effect' refers to the metabolism of a drug before it reaches the systemic circulation. This occurs when a drug is absorbed from the gastrointestinal tract and enters the liver first, where it undergoes metabolism before entering the bloodstream. This process can significantly reduce the bioavailability of the drug. The other choices are incorrect because: A. The initial phase of drug distribution does not specifically refer to metabolism in the liver. B. Rapid absorption in the intestine does not involve metabolism in the liver. C. Rapid excretion through the urinary system does not involve metabolism in the liver.
Therefore, choice D is the correct answer as it specifically relates to the process of metabolism before reaching systemic circulation.

Question 2 of 5

Correct Answer:

Rationale:

Question 3 of 5

Correct Answer:

Rationale:

Question 4 of 5

Correct Answer:

Rationale:

Question 5 of 5

Correct Answer:

Rationale:

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