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ATI Pharmacology Exam 1 Questions

Extract:


Question 1 of 5

The patient is taking low-dose aspirin daily for his heart. The nurse knows only a portion of the medication taken actually reaches the tissue due to what process?

Correct Answer: B

Rationale: The first-pass effect reduces aspirin's systemic availability as the liver metabolizes it after oral administration, decreasing the amount reaching tissues.

Question 2 of 5

The nurse is developing a teaching plan for an elderly patient who will begin taking an antihypertensive drug that causes dizziness and orthostatic hypotension. Which nursing diagnosis is appropriate for this patient?

Correct Answer: D

Rationale: Dizziness and orthostatic hypotension increase fall risk, making 'risk for injury' the priority nursing diagnosis to ensure patient safety.

Question 3 of 5

A clinical drug trial is conducting a study of pharmacokinetics and safety of a drug in healthy individuals. The nurse will assist enrollment of participants into the next phase of the study and will include which subject?

Correct Answer: C

Rationale: Phase II trials test efficacy and safety in patients with the target disease, unlike Phase I, which involves healthy subjects, ensuring relevant therapeutic data.

Question 4 of 5

The nurse gives medication to a patient with a history of liver disease. The nurse will monitor this patient for

Correct Answer: B

Rationale: Liver disease impairs drug metabolism, leading to drug accumulation and increased effects, potentially causing toxicity.

Question 5 of 5

A nurse is caring for a patient who is supposed to receive two drugs at the same time. What is the nurse's priority action?

Correct Answer: B

Rationale: Ensuring drug compatibility is critical when administering multiple drugs simultaneously, especially IV medications, to prevent precipitation or adverse interactions, prioritizing patient safety.

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