ATI RN
ATI Pharmacology Exam 1 Questions
Extract:
Question 1 of 5
The patient is taking low-dose aspirin daily for his heart. The nurse knows only a portion of the medication taken actually reaches the tissue due to what process?
Correct Answer: B
Rationale: The correct answer is B: First-pass effect. The first-pass effect refers to the metabolism of a drug in the liver before it reaches systemic circulation. Aspirin, when taken orally, undergoes extensive metabolism in the liver before reaching the heart tissue, reducing its bioavailability. Distribution (
A) refers to the transportation of a drug within the body after absorption, not the process affecting bioavailability. Reduced absorption (
C) pertains to the amount of drug that enters the bloodstream after administration, not specifically related to liver metabolism. Gastrointestinal circulation (
D) is not a recognized pharmacokinetic process and does not explain the reduced bioavailability of aspirin.
Question 2 of 5
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Question 3 of 5
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Question 4 of 5
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Question 5 of 5
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