ATI RN
ATI Pharmacology Quiz 240 Questions
Extract:
Question 1 of 5
The nurse is caring for a client who is taking simvastatin (Zocor). What should the nurse instruct this client to avoid while taking this medication?
Correct Answer: C
Rationale: The correct answer is C: Grapefruit juice. Grapefruit juice can interfere with the metabolism of simvastatin, leading to increased levels of the drug in the body and potentially causing side effects. It inhibits the enzyme CYP3A4, which is responsible for metabolizing simvastatin. Avoiding grapefruit juice will help maintain the effectiveness and safety of simvastatin therapy.
Choices A, B, and D are incorrect because they do not have a significant interaction with simvastatin. Orange juice and all fruit juices do not have any known interactions with simvastatin. Coenzyme Q10 supplements may actually be beneficial for individuals taking statins.
Question 2 of 5
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Question 3 of 5
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Question 4 of 5
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Question 5 of 5
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