ATI Pharmacology Exam 2 | Nurselytic

Correct Answer: A

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Correct Answer: A: Inhibit cyclooxygenase that is necessary for prostaglandin synthesis.


Rationale: NSAIDs work by inhibiting the enzyme cyclooxygenase (COX), which is essential for the synthesis of prostaglandins. Prostaglandins are lipid compounds that play a crucial role in inflammation, pain, and fever. By blocking COX, NSAIDs reduce the production of prostaglandins, leading to decreased inflammation and pain sensation.

Summary of Incorrect

Choices:
B: Exert direct actions to cause relaxation of smooth muscle - This choice is incorrect because NSAIDs do not directly cause relaxation of smooth muscle. Their primary mechanism of action is through inhibition of prostaglandin synthesis.
C: Suppress prostaglandin activity by blocking tissue receptor sites - This choice is incorrect as NSAIDs work by inhibiting COX, not by blocking tissue receptor sites.
D: Interfere with neuronal pathways associated with prostaglandin action - This choice is incorrect

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