ATI N180 Pharmacology Exam | Nurselytic

Correct Answer: B

Rationale: The correct answer is B: Pinpoint pupils, respiratory depression, and coma. The opioid toxicity triad includes these signs and symptoms: pinpoint pupils due to miosis, respiratory depression leading to hypoventilation, and central nervous system depression ultimately resulting in coma. Pinpoint pupils are a classic sign of opioid overdose due to the drug's effect on the parasympathetic nervous system. Respiratory depression is a life-threatening complication of opioid overdose, leading to hypoxia and potentially respiratory arrest. Coma is the most severe manifestation of opioid toxicity, indicating profound central nervous system depression.

Choices A, C, and D include incorrect signs and symptoms that are not part of the opioid toxicity triad.
Choice A mentions respiratory alkalosis, which is not a typical feature of opioid overdose.
Choice C includes hypertension, which is not commonly seen in opioid toxicity.
Choice D mentions constipation and pupillary dilation, which may occur with chronic opioid use but are not part of the acute overdose presentation.

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