ATI N180 Pharmacology Quiz 2 | Nurselytic

Correct Answer: D

Rationale: The correct answer is D: Ondansetron blocks serotonin receptors in the chemoreceptor trigger zone. Ondansetron is a selective serotonin 5-HT3 receptor antagonist. By blocking these receptors in the chemoreceptor trigger zone, ondansetron inhibits the vomiting reflex triggered by various stimuli, such as chemotherapeutic agents or post-operative nausea.

Choices A, B, and C are incorrect because they all mention agonizing serotonin receptors, whereas ondansetron actually blocks these receptors.
Choice A specifically mentions afferent vagal neurons, which is not the primary site of action for ondansetron.
Choice C mentions dopaminergic receptors, which are not the main target of ondansetron.
Therefore, the correct mechanism of action for ondansetron is to block serotonin receptors in the chemoreceptor trigger zone to prevent nausea and vomiting.

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