ATI RN
ATI RN Fundamental Proctored Exam With NGN Graded Questions
Extract:
Question 1 of 5
A nurse educator is teaching a module on pharmacokinetics to a group of newly licensed nurses. Which of the following statements by a newly licensed nurse indicates an understanding of the 1st-pass effect?
Correct Answer: B
Rationale:
Correct
Answer: B
Rationale:
1. The 1st-pass effect refers to the metabolism of a drug in the liver before it reaches systemic circulation.
2. Medications administered orally undergo first-pass metabolism in the liver, leading to potential inactivation.
3. Administering such meds through nonenteral routes (e.g., intravenous) bypasses the liver, avoiding inactivation.
4.
Choice A discusses receptor activity, not related to the first-pass effect.
5.
Choice C refers to drug elimination rate, not specific to the first-pass effect.
6.
Choice D discusses safety margin and monitoring, not directly related to drug metabolism.
Question 2 of 5
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Question 3 of 5
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Question 4 of 5
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Question 5 of 5
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