ATI RN
ATI Pharmacology Exam 1 Questions
Extract:
Question 1 of 5
A clinical drug trial is conducting a study of pharmacokinetics and safety of a drug in healthy individuals. The nurse will assist enrollment of participants into the next phase of the study and will include which subject?
Correct Answer: C
Rationale: Phase II trials test efficacy and safety in patients with the target disease, unlike Phase I, which involves healthy subjects, ensuring relevant therapeutic data.
Question 2 of 5
The nurse prepares to change a patient's medication from an intravenous to an oral form and notes that the oral form is ordered in a higher dose. The nurse understands that this is due to differences in
Correct Answer: A
Rationale: Oral medications have lower bioavailability due to first-pass metabolism, requiring higher doses than IV to achieve the same effect.
Question 3 of 5
The nurse is developing a teaching plan for an elderly patient who will begin taking an antihypertensive drug that causes dizziness and orthostatic hypotension. Which nursing diagnosis is appropriate for this patient?
Correct Answer: D
Rationale: Dizziness and orthostatic hypotension increase fall risk, making 'risk for injury' the priority nursing diagnosis to ensure patient safety.
Question 4 of 5
Which are responsibilities of the FDA? (Select all that apply.)
Correct Answer: A,B,E
Rationale: The FDA oversees drug testing for safety and efficacy and ensures accurate labeling, but it cannot guarantee no adverse reactions or affordability.
Question 5 of 5
The nurse understands that the length of time needed for a drug to reach the minimum effective concentration (MEC) is the
Correct Answer: B
Rationale: Onset of action is the time from administration to when the drug reaches MEC, initiating its therapeutic effect, influenced by absorption and distribution rates.