ATI RN
ATI Pharmacology Quiz Questions
Extract:
Question 1 of 5
A client with a organ transplant has been placed on methotrexate (Rheumatrex). Which of the following mechanism of actions below describes this medication?
Correct Answer: B
Rationale: Methotrexate inhibits dihydrofolate reductase, blocking folic acid synthesis and thus DNA/RNA replication, crucial for immunosuppression in transplants.
Question 2 of 5
A nurse is caring for a client who is prescribed tetracycline 5 grams daily PO in divided doses every 8 hr. Available is tetracycline 500 mg capsules. How many capsules should the nurse administer per dose?
Correct Answer: B
Rationale: 1.5 g daily ÷ 3 doses = 0.5 g (500 mg) per dose ÷ 500 mg/capsule = 1 capsule per dose.
Question 3 of 5
The nurse is administering an estrogen blocker to a client diagnosed with advanced breast cancer. Which of the following side effects will the nurse caution the client regarding?
Correct Answer: C
Rationale: Estrogen blockers like tamoxifen increase the risk of thromboembolic events due to pro-thrombotic effects, unlike tendon rupture, lymphomas, or photosensitivity.
Question 4 of 5
The nurse understands that neomycin may cause serious adverse effects such as HepatotoxicityCardiotoxicityDermatotoxicityNeurotoxicityOtotoxicityHemotoxicity and HepatotoxicityCardiotoxicityNephrotoxicityDermatotoxicityOtotoxicityHemotoxicity.
Correct Answer: D,G
Rationale: Neomycin, an aminoglycoside, can cause neurotoxicity (e.g., muscle weakness) and nephrotoxicity (kidney damage), particularly in infants, unlike other listed effects.
Question 5 of 5
A nurse is caring for a client who has chronic renal disease and is receiving therapy with epoetin alfa (Epogen). Which of the following laboratory results would the nurse assess for to determine therapeutic effectiveness?
Correct Answer: C
Rationale: Epoetin alfa stimulates red blood cell production, so hemoglobin and hematocrit levels indicate therapeutic effectiveness, unlike liver enzymes, leukocytes, or clotting factors.