ATI N180 Pharmacology Exam

Extract:

Question 1 of 5

A client has a new prescription of spironolactone (Aldactone), and wants to learn about how the mechanism of action of this medication. Which of the following statements should the nurse explain to the client?

A. This medication works in the high-ceiling loop diuretics work in the loop of Henle. It blocks the reabsorption of sodium and chloride and prevents the reabsorption of water, which causes extensive diuresis even with severe renal impairment B. This medication works in the distal tubule to block the reabsorption of sodium and chloride and prevents the reabsorption of water. C. This medication reduces intracranial pressure and intraocular pressure by raising serum osmolality and drawing fluid back into the vascular and extravascular space. D. This medication blocks the action of aldosterone (sodium and water retention), which results in potassium retention and the excretion of sodium and water.

Correct Answer: D

Rationale: The correct answer is D because spironolactone is an aldosterone antagonist, blocking its action in the distal tubule. By inhibiting aldosterone, it promotes potassium retention and the excretion of sodium and water. This mechanism leads to diuresis and helps in conditions like heart failure and hypertension.

Choice A is incorrect as it describes the mechanism of loop diuretics, not spironolactone.
Choice B is incorrect because spironolactone acts in the distal tubule, not the loop of Henle.
Choice C is incorrect as it describes the mechanism of mannitol, not spironolactone.

Question 2 of 5

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Question 3 of 5

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Question 4 of 5

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Question 5 of 5

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ATI N180 Pharmacology Exam | Nurselytic

Nurselytic

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