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Herzing University NSG158 Questions

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What is the primary mechanism of Ibuprofen’s therapeutic action?

Correct Answer: A

Rationale: Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAI
D) that exerts its analgesic and anti-inflammatory effects through reversible inhibition of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes. This reduces prostaglandin synthesis, leading to decreased inflammation, pain, and fever. The improvement in pain and swelling confirms inhibition of prostaglandin-mediated processes. Unlike aspirin, ibuprofen’s COX inhibition is reversible, allowing for shorter duration of platelet effects. Its mechanism underlies its common use in musculoskeletal pain and inflammatory conditions.

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