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Herzing University NSG153 Questions

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What is the primary mechanism of action of Prednisone?

Correct Answer: A

Rationale: Prednisone is a glucocorticoid that exerts its anti-inflammatory effect by suppressing the arachidonic acid pathway. It induces the synthesis of lipocortin, which inhibits phospholipase A2, thereby decreasing the formation of prostaglandins and leukotrienes—major mediators of inflammation. This broad suppression of inflammatory signaling results in reduced tissue edema, erythema, and pain. The delayed but significant improvement over 48 hours aligns with its genomic mechanism of action, making prednisone valuable in autoimmune and allergic conditions.

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