ATI RN
Herzing University NSG151 Questions
Question 1 of 1
What is the mechanism of action of Heparin resulting in this laboratory change?
Correct Answer: A
Rationale: Heparin acts by binding to and enhancing the activity of antithrombin III, which in turn inhibits clotting factors IIa (thrombin) and Xa. This leads to prolongation of activated partial thromboplastin time (aPTT), indicating effective anticoagulation. It does not directly inhibit thrombin or affect vitamin K metabolism. The rapid increase in aPTT following administration reflects the drug’s immediate anticoagulant effect. Heparin is essential for the prevention and treatment of thromboembolic disorders, particularly in acute care settings.
Question 2 of 1
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