ATI RN
Herzing University NSG149 Questions
Question 1 of 1
Which mechanism best accounts for Metformin’s glucose-lowering effect?
Correct Answer: A
Rationale: Metformin lowers blood glucose by suppressing hepatic gluconeogenesis, increasing peripheral glucose uptake, and enhancing insulin sensitivity in muscle and adipose tissue. It does not stimulate insulin secretion, distinguishing it from sulfonylureas. The observed reduction in blood glucose from 10.8 to 7.4 mmol/L reflects effective metabolic regulation. Metformin’s mechanism also includes improvement of lipid profiles and mild inhibition of intestinal glucose absorption, but its primary action remains the inhibition of hepatic glucose production.
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