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Herzing University NSG143 Questions

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Which mechanism explains the effect of Metoprolol on heart rate?

Correct Answer: A

Rationale: Metoprolol is a cardioselective beta-1 adrenergic receptor blocker that reduces heart rate, myocardial contractility, and cardiac output by inhibiting sympathetic stimulation. The drop from 98 to 72 bpm demonstrates effective beta-blockade. It does not act by blocking calcium channels or stimulating alpha receptors. Its selective beta-1 antagonism makes it particularly useful for treating hypertension, angina, and certain tachyarrhythmias while minimizing bronchoconstrictive effects associated with nonselective beta-blockers.

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