ATI RN
Herzing University NSG142 Questions
Question 1 of 1
Following Warfarin administration, the patient’s INR increased. What is the pharmacological basis of this change?
Correct Answer: A
Rationale: Warfarin exerts its anticoagulant effect by inhibiting vitamin K epoxide reductase, which reduces the synthesis of vitamin K-dependent clotting factors II, VII, IX, and X. The increase in INR (International Normalized Ratio) reflects effective anticoagulation. Warfarin does not directly inhibit thrombin or activate fibrinolysis; instead, it prevents clot formation through decreased coagulation factor activity. This mechanism underscores the importance of regular INR monitoring to maintain therapeutic anticoagulation while avoiding bleeding risks.
Question 2 of 1
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