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Herzing University NSG136 Questions

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Following Metformin administration, the patient’s glucose remained stable. What mechanism supports this stability?

Correct Answer: B

Rationale: Metformin, a biguanide, is the first-line pharmacologic agent for type 2 diabetes management. It works by decreasing hepatic gluconeogenesis (glucose production) and increasing insulin sensitivity in peripheral tissues such as muscle and adipose tissue. The observed stabilization of blood glucose at 6.5 mmol/L confirms its therapeutic action without causing hypoglycemia. Unlike sulfonylureas, it does not stimulate insulin release, and it does not function primarily by altering gastric motility or carbohydrate absorption. This mechanism makes Metformin effective for maintaining euglycemia and improving metabolic profiles while minimizing hypoglycemic risk.

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