ATI RN
Herzing University NSG135 Questions
Question 1 of 1
After Amlodipine administration, blood pressure decreased to 118/76 mmHg. What mechanism explains this effect?
Correct Answer: B
Rationale: Amlodipine is a dihydropyridine calcium channel blocker that acts by inhibiting calcium entry through L-type calcium channels in vascular smooth muscle. This results in relaxation of arterial walls, decreased peripheral vascular resistance, and subsequent reduction in blood pressure. The observed normalization of BP (118/76 mmHg) reflects this vasodilatory mechanism. Unlike beta-blockers, which reduce cardiac workload, or diuretics, which decrease volume, Amlodipine’s primary effect is peripheral vasodilation without significant alteration in heart rate or renal output. Its antihypertensive efficacy is particularly advantageous for long-term blood pressure management due to its once-daily dosing and sustained action.
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