With respect to her hyperglycaemia, what is the best advice you should give?

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Pediatric Dosing Practice Questions Questions

Question 1 of 5

With respect to her hyperglycaemia, what is the best advice you should give?

Correct Answer: A

Rationale: A 14-year-old with type 1 diabetes on an insulin pump has hyperglycemia (20.2 mmol/L) and mild ketosis (1.2 mmol/L), but is otherwise well. A correction bolus of rapid-acting insulin via the pump (Choice A) is the standard approach to correct hyperglycemia, leveraging the pump’s precision and existing functionality. Using a syringe or pen (Choice B) is unnecessary unless pump failure is suspected, which isn’t indicated. Long-acting insulin (Choice C) is inappropriate for acute correction. Exercise and water (Choice D) risk worsening ketosis without insulin. The pump bolus is the safest, most effective option.

Question 2 of 5

A female child was diagnosed to have selective IgA deficiency. She suffered from an anaphylactic reaction after a blood transfusion that was properly matched. The appropriate blood for her transfusion should be:

Correct Answer: C

Rationale: Selective IgA deficiency can trigger anaphylaxis to IgA in blood products; washed erythrocytes remove plasma IgA, preventing reactions (AABB). Other options (A-D) contain IgA and risk reaction.

Question 3 of 5

Most frequent humoral immunologic abnormality in patients with ataxia-telangiectasia is:

Correct Answer: B

Rationale: Selective IgA deficiency is most common in ataxia-telangiectasia, impairing mucosal immunity (NORD). Other options (A, C-E) are less typical.

Question 4 of 5

A child is being treated for hypernatremic dehydration. Suddenly, she develops seizures. Most likely cause of seizure is:

Correct Answer: A

Rationale: Rapid correction of hypernatremia shifts water into brain cells , causing edema and seizures (UpToDate). B-E don’t match pathophysiology.

Question 5 of 5

Best drug of choice for a severe listeria infection is:

Correct Answer: C

Rationale: Ampicillin plus gentamicin is the standard for severe Listeria infections, enhancing efficacy (IDSA). A-D are suboptimal.

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