ATI LPN
LPN Pharmacology Multiple Choice Questions Questions
Question 1 of 5
Criteria for choosing an effective drug for a disorder include:
Correct Answer: B
Rationale:
Choice B is correct because nationally recognized guidelines provide evidence-based recommendations for effective drug selection, ensuring treatment aligns with proven standards.
Choice A is incorrect as patient preference alone lacks scientific basis and could lead to suboptimal therapy.
Choice C is wrong because basing decisions on sample availability prioritizes convenience over clinical appropriateness.
Choice D is also incorrect since DEA guidelines focus on controlled substances, not general criteria for selecting effective drugs for disorders.
Question 2 of 5
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
Correct Answer: D
Rationale:
Choice D is correct because peak and trough levels for phenytoin are measured to ensure concentrations stay within the therapeutic range, avoiding toxicity or subtherapeutic effects due to its narrow range.
Choice A is incorrect as a wide range wouldn't require such precise monitoring.
Choice B is wrong because duration of use doesn't dictate peak/trough testing.
Choice C is incorrect since receptor saturation correlation isn't the primary reason; it's about therapeutic levels.
Question 3 of 5
Drugs are metabolized mainly by the liver via phase I or phase II reactions. The purpose of both of these types of reactions is to:
Correct Answer: C
Rationale:
Choice C is correct because phase I (oxidation, reduction) and phase II (conjugation) reactions in the liver transform drugs into water-soluble forms for excretion by organs like the kidneys, aiding elimination.
Choice A is incorrect as prodrug activation is intentional, not inactivation.
Choice B is wrong because metabolism prepares drugs for excretion, not membrane crossing.
Choice D is incorrect since ionization is a means to the end of excretion, not the primary purpose.
Question 4 of 5
Drug antagonism is best defined as an effect of a drug that:
Correct Answer: B
Rationale:
Choice B is correct because drug antagonism occurs when one drug's effect is altered (usually reduced) by another, a classic interaction like beta blockers countering adrenaline.
Choice A is incorrect as dependence isn't antagonism.
Choice C is wrong because metabolism timing isn't the definition.
Choice D is incorrect since it's a consequence, not the defining feature.
Question 5 of 5
An NP would prescribe the liquid form of ibuprofen for a 6-year-old child because:
Correct Answer: B
Rationale:
Choice B is correct because a 6-year-old may struggle to swallow pills, making liquid ibuprofen easier to administer and ensuring compliance.
Choice A is incorrect as liquid forms aren't inherently less irritating—irritation depends on the drug.
Choice C is wrong because liquids still undergo first-pass metabolism when swallowed.
Choice D is incorrect since dosing frequency depends on pharmacokinetics, not form.