Questions 78

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LPN Nursing Questions Related to Pharmacology Questions

Question 1 of 5

Clinical judgment in prescribing includes:

Correct Answer: S

Rationale:
Choice A is correct because clinical judgment involves balancing efficacy, safety, and cost to ensure patients can afford and adhere to treatment, which is critical for successful outcomes.
Choice B is incorrect as always choosing the newest medication ignores evidence-based practice; newer drugs may lack long-term data or be unnecessarily expensive.
Choice C is wrong because distributing samples isn't a sustainable prescribing strategy and may not meet ongoing needs.
Choice D is also incorrect since mandating generics could compromise efficacy if a brand-name drug is clinically necessary.

Question 2 of 5

Signs of controlled substance misuse include:

Correct Answer: D

Rationale:
Choice D is correct because early refills, lost prescription claims, and multiple prescribers are classic misuse signs, per DEA and clinical red flags.
Choice A is incorrect alone as it's one sign.
Choice B is wrong by itself because lost reports are just part.
Choice C is incorrect solo since multiple prescribers is only one indicator.

Question 3 of 5

Drugs that are affected by genetic polymorphisms of UGT1A1 include:

Correct Answer: B

Rationale:
Choice B is correct because irinotecan's active metabolite is glucuronidated by UGT1A1; poor function increases toxicity, requiring genetic consideration.
Choice A is incorrect as warfarin's metabolism is via CYP2C9, not UGT1A1.
Choice C is wrong because acetaminophen uses other UGT enzymes, not specifically UGT1A1 critically.
Choice D is incorrect since only irinotecan is notably affected by UGT1A1 polymorphisms.

Question 4 of 5

The elderly are at high risk of ADRs due to:

Correct Answer: D

Rationale:
Choice D is correct because an age-related decline in renal function slows drug excretion, increasing ADR risk as drugs accumulate.
Choice A is incorrect as muscle mass decreases with age, not increases.
Choice B is wrong because studies are often limited in the elderly, not extensive.
Choice C is incorrect since the blood-brain barrier's permeability doesn't typically lessen, and higher doses aren't standard.

Question 5 of 5

The primary care NP sees a 5-year-old child for a prekindergarten physical examination. The child's parents do not have immunization records, and a local record search does not provide proof of vaccinations, although the parent thinks the child may have had some vaccines several years ago. The NP's initial action will be to:

Correct Answer: A

Rationale: The correct answer is A because without records, assuming unvaccinated and starting the series ensures protection.
Choice B is incorrect (titers not practical initially).
Choice C is wrong (single doses insufficient).
Choice D is inaccurate (registry already checked).

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