ATI LPN
NCLEX PN Pharmacology Questions Questions
Question 1 of 5
A patient's nutritional intake and lab work reflects hypoalbuminemia. Prescribing implications include:
Correct Answer: C
Rationale:
Choice C is correct because hypoalbuminemia reduces albumin, which binds drugs in plasma; this increases free drug levels, affecting distribution and potentially raising efficacy or toxicity risks, a key prescribing consideration.
Choice A is incorrect as more drug isn't needed—free levels are already higher.
Choice B is wrong because increasing dosage could lead to overdose, not address distribution.
Choice D is incorrect since hypoalbuminemia does impact prescribing, and monitoring alone doesn't adjust for altered pharmacokinetics.
Question 2 of 5
The U.S. Food and Drug Administration regulates:
Correct Answer: B
Rationale:
Choice B is correct because the FDA regulates drug labeling, ensuring safety and efficacy information is accurate for all prescription and OTC drugs.
Choice A is incorrect as prescribing is governed by state boards, not the FDA.
Choice C is wrong because off-label use is allowed but not regulated by the FDA.
Choice D is incorrect since educational offerings fall under other entities, not FDA control.
Question 3 of 5
Steady state is:
Correct Answer: B
Rationale:
Choice B is correct because steady state occurs when drug input (absorption) equals output (excretion), maintaining constant levels over time.
Choice A is incorrect as absorption exceeding excretion describes initial dosing, not steady state.
Choice C is wrong because steady state can be therapeutic or toxic, not just below toxicity.
Choice D is incorrect since only B defines steady state accurately.
Question 4 of 5
A 40-year-old woman asks the primary care NP what she can do to minimize her risk of osteoporosis. She takes 800 mg of calcium and drinks 2 cups of skim milk each day. The NP should recommend that she:
Correct Answer: B
Rationale: The correct answer is B because high caffeine reduces calcium absorption, increasing osteoporosis risk.
Choice A is incorrect (fat aids absorption).
Choice C is wrong (high protein reduces absorption).
Choice D is inaccurate (all sodas reduce calcium).
Question 5 of 5
A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n):
Correct Answer: A
Rationale:
Choice A is correct because neutropenia from Silvadene is a type II (cytotoxic) hypersensitivity reaction, where antibodies target and destroy white blood cells.
Choice B is incorrect as immune complex (type III) reactions cause inflammation, not neutropenia.
Choice C is wrong because immediate (type I) reactions are allergic, not cytotoxic.
Choice D is incorrect since delayed (type IV) reactions involve T-cells, not antibody-mediated blood cell loss.