ATI LPN
NCLEX PN Questions on Pharmacology Questions
Question 1 of 5
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir of the drug. Storage reservoirs:
Correct Answer: C
Rationale:
Choice C is correct because IM storage reservoirs, like Depo Provera, release the drug slowly over time, extending its duration of action and availability in the body.
Choice A is incorrect as reaching target tissue depends on distribution, not just the reservoir.
Choice B is wrong because loading doses are for rapid therapeutic levels, not reservoirs, which provide sustained release.
Choice D is incorrect since reservoirs are typically in muscle or fat, not collagen tissues.
Question 2 of 5
Drugs administered via IV:
Correct Answer: B
Rationale:
Choice B is correct because IV drugs bypass absorption, entering the bloodstream directly and beginning distribution immediately, ensuring rapid onset.
Choice A is incorrect as lipid solubility matters for oral absorption, not IV, where absorption isn't a factor.
Choice C is wrong because ionization affects absorption in other routes, not IV delivery.
Choice D is incorrect since pinocytosis is a cellular uptake mechanism, not relevant to IV administration.
Question 3 of 5
Actions taken to reduce drug-drug interaction problems include all of the following EXCEPT:
Correct Answer: C
Rationale:
Choice C is incorrect because prescribing a third drug to counteract interactions adds complexity and risk, not a standard reduction strategy, making it the exception.
Choice A is correct as reducing one drug's dose minimizes interaction effects.
Choice B is right because staggering administration times can avoid peak interaction.
Choice D is correct since lowering both doses reduces interaction potential.
Question 4 of 5
An advantage of prescribing a sublingual medication is that the medication is:
Correct Answer: A
Rationale:
Choice A is correct because sublingual administration allows rapid absorption via the rich blood supply under the tongue, bypassing first-pass metabolism for quick onset.
Choice B is incorrect as excretion rate isn't directly affected by this route.
Choice C is wrong because minimal metabolism is a benefit, not the defining advantage.
Choice D is incorrect since distribution isn't equal—it's systemic, not a primary advantage.
Question 5 of 5
The therapeutic goals when prescribing include(s):
Correct Answer: D
Rationale:
Choice D is correct because therapeutic goals can be curative (healing), palliative (symptom relief), or preventive (disease avoidance), depending on the patient's condition, making all options valid.
Choice A is incorrect as it's only one goal, not all.
Choice B is wrong because it excludes curative and preventive aims.
Choice C is incorrect since it misses curative and palliative goals.